WebNov 6, 2024 · Phospho-AXL was significantly decreased in response to both R428 and cabozantinib treatment even though total AXL was likely induced by both inhibitors. Phospho-MET seemed to be decreased with increased amounts of cabozantinib, whereas it increased with increased amounts of R428. WebApr 12, 2024 · Human Phospho-Axl Capture Antibody (Part 841644) - Each vial contains 1440 μg/mL of mouse anti-human Axl antibody when reconstituted with 200 μL of PBS. Anti-pY-HRP A (Part 841420) - Each vial contains 50 μL of mouse anti-human phospho-tyrosine conjugated to HRP. Immediately before use, dilute the Anti-pY-HRP A in IC Diluent #14 to …
Phospho Axl Y779 R&D Systems Bioz
WebPhospho-Axl (Y779) ELISA Kit (ab279743) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in human cell … WebMay 26, 2024 · This effective silencing of the phospho-AXL target thus demonstrated that aptamer specificity and bioavailability can be improved by the chemical modification of existing aptamers for phospho-AXL. These results lay the foundation for the translation of these aptamer candidates and companion biomarkers to the clinic. pscs 是什么
Phospho-AXL (Tyr698, Tyr702, Tyr703) Rabbit anti …
WebAXL is a receptor tyrosine kinase with a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. AXL stimulation has been described to drive cellular … Phospho-Axl (Tyr702) (D12B2) Rabbit mAb detects endogenous levels of Axl only when phosphorylated at Tyr702. This antibody may also cross-react with other overexpressed, related tyrosine-phosphorylated tyrosine kinases, such as EGFR. Species Reactivity: Human Species predicted to react based on 100% sequence homology: WebLigand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, AXL binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2. horse rubber stamps for card making