Jpan j clin oncol. 2009 39:244-250

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Nettet1. des. 2009 · Purpose: Targeted therapy with the humanized monoclonal antibody trastuzumab has become a mainstay for human epidermal growth factor receptor 2 (HER2) -positive breast cancer (BC). The mechanisms of action of trastuzumab have not been fully elucidated, and data available to date are reviewed here. The impact of the … NettetJ Clin Oncol. 2009;27(26):4247–4253. 10. Camidge DR, Kono SA, Flacco A, et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res. 2010;16(22):5581–5590. 11.

Acute leukemias in pregnant women: Results of a retrospective …

Nettet25. feb. 2010 · Phase II Study of Gemcitabine Chemotherapy Alone for Locally Advanced Pancreatic Carcinoma: JCOG0506 Japanese Journal of Clinical Oncology Oxford … NettetIssue 13 May 1 2009 (pp. 2111-2305) Issue 12 April 20 2009 (pp. 1925-2110) Issue 11 April 10 2009 (pp. 1735-1923) norfolk naval air station zip code

Olaparib for metastatic castration-resistant prostate cancer OTT

Nettet20. jan. 2024 · Purpose: Pembrolizumab demonstrated antitumor activity and safety in the phase II KEYNOTE-224 trial in previously treated patients with advanced hepatocellular carcinoma (HCC). KEYNOTE-240 evaluated the efficacy and safety of pembrolizumab in this population. Patients and methods: This randomized, double-blind, phase III study … Nettet20. nov. 2009 · doi: 10.1200/jco.2009.23.1431 Abstract Purpose: Previous studies in non-small-cell lung cancer (NSCLC) have demonstrated a wide variation in responsiveness to epidermal growth factor receptor (EGFR) -targeting agents and in genetic aberrancies of the EGFR pathway according to ethnic background, most notably a higher frequency of … NettetThe effect of MGMT promoter methylation on OS was explored in 30 studies by univariate analysis and in 30 studies by multivariate analysis. The combined HR was 0.48 (95% CI 0.44, 0.52) and 0.42 (95% CI 0.38, 0.45), respectively. Conclusion: In each subgroup divided by areas, the prognostic significance still remained highly significant. norfolk my school login

Development of anaplastic lymphoma kinase (ALK) inhibitors and ...

Journal of Clinical Oncology

NettetCancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the Monitoring of Cancer Incidence in Japan (MCIJ) project A … NettetJ Clin Oncol 27(31):5124–5130 CrossRefPubMedPubMedCentral Roh MS, Colangelo LH, O’Connell MJ, Yothers G, Deutsch M, Allegra CJ, Kahlenberg MS, Baez-Diaz L, Ursiny CS, Petrelli NJ, Wolmark N (2009) Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R‑03. norfolk naval base auto hobby shopNettet15. jul. 2013 · Immunotoxins are antibody-toxin bifunctional molecules that rely on intracellular toxin action to kill target cells. Target specificity is determined via the binding attributes of the chosen antibody. Mostly, but not exclusively, immunotoxins are purpose-built to kill cancer cells as part of novel treatment approaches. Other applications for … norfolk nas space a

"NettetMicrotubule inhibitor-based antibody–drug conjugates for cancer therapy Kelsey Klute,1,* Eleni Nackos,1,* Shinsuke Tasaki,1 Daniel P Nguyen,2 Neil H Bander,2 Scott T Tagawa1,2 1Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY, USA; 2Department of Urology, Weill Cornell … " - Jpan j clin oncol. 2009 39:244-250

Jpan j clin oncol. 2009 39:244-250

NettetThe second modulator, potassium oxonate (Oxo), localizing in mucosal cells of the gastrointestinal (GI) tract after oral administration, reduces the incidence of GI toxicities … Nettet7. jan. 2024 · A primary analysis of a multicenter, prospective, single-arm, confirmatory trial of hypofractionated whole breast irradiation after breast-conserving surgery in Japan: …

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NettetIntroduction. Adult T-cell leukemia/lymphoma (ATLL), a highly aggressive peripheral T-cell lymphoma (PTCL) caused by human T-cell lymphotropic virus type-1, has a very poor prognosis. 1–4 In a retrospective analysis of 807 patients newly diagnosed with acute- and lymphoma-type ATLL between January 2000 and May 2009, the median overall … Nettet8. okt. 2012 · In the November 20, 2009, issue of Journal of Clinical Oncology, we reported the results of our first analysis of a phase I/II study of concurrent …

Nettet2. feb. 2015 · A randomized controlled Phase III trial comparing 2-weekly docetaxel combined with cisplatin plus fluorouracil (2-weekly DCF) with cisplatin plus fluorouracil … Nettet10. nov. 2008 · With a median follow-up of 109 months (range, 10 to 244), 170 (28%) developed transformation, 107 (63%) based on biopsy confirmation. The annual risk of transformation was 3% continuously through 15 years. A multivariate analysis of clinical factors at diagnosis identified advanced stage as the only predictor of future …

NettetThese early, promising results of olaparib in prostate cancer led to the landmark, multicenter Phase II TOPARP-A trial in 2015 which evaluated olaparib in 50 patients with mCRPC who progressed after one or two regimens of chemotherapy. 20 Forty-nine of 50 (98%) patients had received a novel hormonal agent (abiraterone or enzalutamide), … NettetNucleic Acids Research, 1994, Vol. 22, No. 1Jpn J Clin Oncol 1997;27(3) 123 expressed as P < 0.001 or P < 0.0001. Both ‘p’ and ‘P’ are allowed, although the international …

NettetDepartment of Radiation Oncology, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China. Tel +86 28 8542 3278. Fax +86 28 8542 2952. Email [email protected]. Abstract: Nasopharyngeal carcinoma (NPC) is rare in Western countries, but its incidence in China and Southeast Asia is notably high.

Nettet2. nov. 2015 · GI stromal tumor (GIST) is one of the most common single types of soft tissue sarcoma. 1 GIST usually arises from the GI tract and rarely, at other intra-abdominal sites. Approximately 60% of GISTs are cured with surgery, but metastases are frequent. 2 The malignancy potential of GIST varies greatly. 3,4 Several risk-stratification tools are … how to remove linked devices on whatsappNettet23. apr. 2024 · Deoxyribonucleic acid repair deficiency is emerging as a joint mechanism for breast cancer and reproductive aging. Recent studies showed that ovarian reserve may be lower in women with BRCA (g … norfolk naval base cac officeNettet12. apr. 2024 · Journal of Clinical Oncology (JCO) is a high-impact, peer-reviewed medical journal that publishes significant clinical oncology research along with editorials, … how to remove linked file in illustratorNettet3. okt. 2016 · The remaining patient (a 39-year-old woman), who was diagnosed with leiomyosarcoma of the gingiva in a radiation field of RT-DeVIC, had received consolidative high-dose chemotherapy followed by autologous HSCT. In the other patients, there was no apparent association with irradiated volume. how to remove linked files in wordNettetInt J Radiat Oncol Biol Phys. 2002;52(2):283–293. 97. Dikken JL, Jansen EP, Cats A, et al. Impact of the extent of surgery and postoperative chemoradiotherapy on recurrence patterns in gastric cancer. J Clin Oncol. 2010;28(14):2430–2436. 98. norfolk naturalists societyNettet10. mai 2024 · The median age was 49.0 years (range, 19-79), and the majority were ypN+ with Ki-67 ≤ 15%; 59.4% of patients had a clinical pathological staging-estrogen receptor grading score ≥ 3. 50.1% received aromatase inhibitor, and 33% of premenopausal women received a luteinizing hormone releasing hormone analog in addition to either tamoxifen … how to remove linkedin from microsoft teamsNettetAnn Surg Oncol. 2007;14(2):954–959. 35. Yang H, Liu H, Chen Y, et al. Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): a Phase III multicenter, randomized, open-label clinical trial. J Clin Oncol. 2024;36(27):2796–2803. norfolk naval base auto auction