WebThe first CHK1 inhibitor was a staurosporine derivative, UCN-01, (Fig. 11) that inhibits several kinases, including CHK1.Consistent with a role in CHK1 inhibition UCN-01 reduced radiation-induced degradation of Cdc25A, abrogated doxorubicin-induced G2/M arrest, and potentiated cisplatin and camptothecin cytotoxicity. 260 Further analogues of UCN-01 … Web请访问 CellSignal.com，查看我们关于“抗体对”的资料，包括适合 ICW 的胞内抗体对等。CST - 客户满意是我们的首要任务。 ... PhosphoPlus ® Chk1 (Ser317) Antibody Duet

抗体对：适合 ICW 的胞内抗体对 Cell Signaling Technology

WebChk1 (G-4) is a mouse monoclonal antibody raised against amino acids 1-476 representing full length Chk1 of human origin. PRODUCT Each vial contains 200 µg IgG 2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. Chk1 (G-4) is available conjugated to agarose (sc-8408 AC), 500 µg/0.25 ml WebAfter that, cells were incubated at 4°C for 24 h with anti-γ-H2AX (#2577; CST). FITC (#111–095-144; Jackson)-labeled second antibody was added and the cells were incubated for 1 h. DAPI was added and the cells were incubated in the dark for 5 min, then fluorescent mounting medium (#4866-20; Fluorescent Mounting Medium) was added, and the ... how buy audible books

SANTA CRUZ BIOTECHNOLOGY, INC. Chk1 (G-4): sc-8408

WebJun 15, 2000 · Chk1, an evolutionarily conserved protein kinase, has been implicated in cell cycle checkpoint control in lower eukaryotes. By gene disruption, we show that CHK1 deficiency results in a severe proliferation defect and death in embryonic stem (ES) cells, and peri-implantation embryonic lethality in m … WebSerine/threonine-protein kinase Chk1, Cell cycle checkpoint kinase, Checkpoint kinase-1, CHK1 checkpoint homolog, CHK1_HUMAN. UniProt Code History ... Gene Synonyms CHEK1, CHK1. Supplier also known as CST, Cell Signalling, New England Biolabs. View additional product information. Experiments from the literature. Loading published … WebOct 26, 2024 · This gene encodes a component of the CST complex. This complex plays an essential role in protecting telomeres from degradation. This protein also forms a heterodimer with the CST complex subunit STN1 to form the enzyme alpha accessory factor. ... Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in … how many palindrome numbers are in 10 to 1000